TFAI™（Turbulent Flow Aseptic Isolator）是 ESCO 的紊流式無菌隔離器，採用紊流（turbulent flow）氣流設計，提供符合無菌製程要求的隔離操作環境。適用於製藥場域的無菌充填、小批量無菌配製與需要完全隔離的無菌操作。可配置正壓（無菌保護）或負壓（操作人員保護）運行模式。
詳細規格請參閱本頁「規格」分頁。報價與客製化評估請洽原拓科技。
製藥無菌充填
需要在完全隔離環境中進行藥品充填的小批量製程。正壓配置可維持腔體內無菌環境，即使屏障系統有微小滲漏也是從內向外（保護產品）。
小批量無菌配製
研發階段或小量生產的無菌藥品配製。紊流式氣流在操作區域內提供均勻的空氣品質分佈。
需要紊流氣流環境的操作
部分製程對氣流方向的要求是「均勻分佈」而非「單向流」，TFAI™ 的紊流設計適合這類應用。
細胞治療製程
細胞處理的某些步驟需要在無菌隔離環境中進行，TFAI™ 的隔離設計可降低交叉污染風險。
TFAI™ 在 ESCO Class III 產品線中定位為「製藥無菌製程專用的紊流式隔離器」，與 Airstream Class III（BSL 微生物防護）和 CBI-III / SCI Class III（密封隔離器）的應用場景有所區隔。TFAI™ 的紊流氣流設計與正壓配置選項更適合以「產品無菌保護」為主軸的製藥場景。四款設備的完整比較請見 Class III 生物安全櫃 子分類頁。
TFAI™ 的安裝條件依配置模式（正壓/負壓、循環式/全排式）而異，全排式配置需硬管直連排風系統。建議在採購評估階段就與原拓討論製程需求和設施條件。
如需 TFAI™ 的報價、客製化配置討論或整體實驗室建置規劃，歡迎聯繫原拓科技。
Esco Turbulent Flow Aseptic Isolator（TFAI）是一款獨立式隔離器，符合最嚴格的法規要求。該隔離器具備自動氣流和壓力控制，確保在執行測試和其他需要相同環境參數的過程中，能夠提供安全、潔淨且無菌的環境。TFAI具備滿足A級湍流環境的能力，為產品、操作人員和環境之間提供高度的隔離保護。
General Specifications Turbulent Flow Aseptic | TFA-2G | TFAI-3G | TFAI-4G | |
No. of Chambers | 2 (1 Process Chamber and 1 Pass Chamber) | |||
Nominal Size Main Chamber (Width) | 1200 mm (47.2”) | 1600 mm (62.9”) | 2000 mm (78.7”) | |
External Dimensions | With BIBO | 1200 mm x 1100 mm x 3000 mm (47.2” x 43.3” x 118.1”) | 1600 mm x 1100 mm x 3000 mm (62.9” x 43.3” x 118.1”) | 2000 mm x 1100 mm x 3000 mm (78.7” x 43.3” x 118.1”) |
Without BIBO | 1200 mm x 1100 mm x 2600 mm (47.2” x 43.3” x 102.4”) | 1600 mm x 1100 mm x 2600 mm (62.9” x 43.3” x 102.4”) | 2000 mm x 1100 mm x 2600 mm (78.7” x 43.3” x 102.4”) | |
With Adjustable Base Stand (Min) | 1200 mm x 1100 mm x 2300 mm (47.2” x 43.3” x 90.6”) | 1600 mm x 1100 mm x 2300 mm (62.9” x 43.3” x 90.6”) | 2000 mm x 1100 mm x 2300 mm (78.7” x 43.3” x 90.6”) | |
With Adjustable Base Stand (Max) | 1200 mm x 1100 mm x 2700 mm (47.2” x 43.3” x 106.3”) | 1600 mm x 1100 mm x 2700 mm (62.9” x 43.3” x 106.3”) | 2000 mm x 1100 mm x 2700 mm (78.7” x 43.3” x 106.3) | |
External Dimensions | With BIBO | 2465 mm x 1100 mm x 3000 mm (97.0” x 43.3” x 118.1”) | 2865 mm x 1100 mm x 3000 mm (112.8” x 43.3” x 118.1”) | 3265 mm x 1100 mm x 3000 mm (128.5” x 43.3” x 118.1”) |
Without BIBO | 2465 mm x 1100 mm x 2600 mm (97.0” x 43.3” x 102.4”) | 2865 mm x 1100 mm x 2600 mm (112.8” x 43.3” x 102.4”) | 3265 mm x 1100 mm x 2600 mm (128.5” x 43.3” x 102.4”) | |
With Adjustable Base Stand (Min) | 2465 mm x 1100 mm x 2300 mm (97.0” x 43.3” x 90.6”) | 2865 mm x 1100 mm x 2300 mm (112.8” x 43.3” x 90.6”) | 3265 mm x 1100 mm x 2300 mm (128.5” x 43.3” x 90.6”) | |
With Adjustable Base Stand (Max) | 2465 mm x 1100 mm x 2700 mm (97.0” x 43.3” x 106.3”) | 2865 mm x 1100 mm x 2700 mm (112.8” x 43.3” x 106.3”) | 3265 mm x 1100 mm x 2700 mm (128.5” x 43.3” x 106.3”) | |
External Dimensions | With BIBO | 2065 mm x 1100 mm x 3000 mm (81.3” x 43.3” x 118.1”) | 2465 mm x 1100 mm x 3000 mm (97.0” x 43.3” x 118.1”) | 2865 mm x 1100 mm x 3000 mm (112.8” x 43.3” x 118.1”) |
Without BIBO | 2065 mm x 1100 mm x 2600 mm (81.3” x 43.3” x 102.4”) | 2465 mm x 1100 mm x 2600 mm (97.0” x 43.3” x 102.4”) | 2865 mm x 1100 mm x 2600 mm (112.8” x 43.3” x 102.4”) | |
With Adjustable Base Stand (Min) | 2065 mm x 1100 mm x 2300 mm (81.3” x 43.3” x 90.6”) | 2465 mm x 1100 mm x 2300 mm (97.0” x 43.3” x 90.6”) | 2865 mm x 1100 mm x 2300 mm (112.8” x 43.3” x 90.6”) | |
With Adjustable Base Stand (Max) | 2065 mm x 1100 mm x 2700 mm (81.3” x 43.3” x 106.3”) | 2465 mm x 1100 mm x 2700 mm (97.0” x 43.3” x 106.3”) | 2865 mm x 1100 mm x 2700 mm (112.8” x 43.3” x 106.3”) | |
Internal Dimensions (W x D x H) | 1192 mm x 1080 mm x 842 mm (46.9” x 42.5” x 33.1”) | 1592 mm x 1080 mm x 842 mm (62.7” x 42.5” x 33.1”) | 1992 mm x 1080 mm x 842 mm | |
Chamber Sheet Metal | Stainless Steel Type 316L (interior) Stainless Steel Type 304 (exterior) | |||
Filter Type | ULPA filter (U15) | |||
Support Frame & Service Housing | Stainless Steel Type 304 | |||
Chamber Environment | ISO Class 5 (Grade A) | |||
Airflow Type | Turbulent | |||
Lighting Intensity | ≥ 500 Lux (≥ 47 foot-candles) | |||
Noise Level | ≤ 65 dBA | |||
Electrical Requirement | AC 230-240 V, 50/60 Hz, 1 Ph, 25A | |||
General Specifications Turbulent Flow Aseptic | TFA-2G | TFAI-3G | TFAI-4G | ||
No. of Chambers | 2 (1 Process Chamber and 1 Pass Chamber) | ||||
Nominal Size Main Chamber (Width) | 1200 mm (47.2”) | 1600 mm (62.9”) | 2000 mm (78.7”) | ||
External Dimensions (W x D x H) | With Pod Flange | With BIBO | 1200 mm x 780 mm x 3000 mm (47.2” x 30.7” x 118.1”) | 1600 mm x 780 mm x 3000 mm (62.9” x 30.7” x 118.1”) | 2000 mm x 780 mm x 3000 mm (78.7” x 30.7” x 118.1”) |
Without BIBO | 1200 mm x 780 mm x 2600 mm (47.2” x 30.7” x 102.4”) | 1600 mm x 780 mm x 2600 mm (62.9” x 30.7” x 102.4”) | 2000 mm x 780 mm x 2600 mm (78.7” x 30.7” x 102.4”) | ||
With Adjustable Base Stand (Min) | 1200 mm x 780 mm x 2300 mm (47.2” x 30.7” x 90.6”) | 1600 mm x 780 mm x 2300 mm (62.9” x 30.7” x 90.6”) | 2000 mm x 780 mm x 2300 mm (78.7” x 30.7” x 90.6”) | ||
With Adjustable Base Stand (Max) | 1200 mm x 780 mm x 2700 mm (47.2” x 30.7” x 106.3”) | 1600 mm x 780 mm x 2700 mm (62.9” x 30.7” x 106.3”) | 2000 mm x 780 mm x 2700 mm (78.7” x 30.7” x 106.3”) | ||
Without Pod Flange | With BIBO | 1200 mm x 695 mm x 3000 mm (47.2” x 27.4” x 118.1”) | 1600 mm x 695 mm x 3000 mm (62.9” x 27.4” x 118.1”) | 2000 mm x 695 mm x 3000 mm (78.7” x 27.4” x 118.1”) | |
Without BIBO | 1200 mm x 695 mm x 2600 mm (47.2” x 27.4” x 102.4”) | 1600 mm x 695 mm x 2600 mm (62.9” x 27.4” x 102.4”) | 2000 mm x 695 mm x 2600 mm (78.7” x 27.4” x 102.4”) | ||
With Adjustable Base Stand (Min) | 1200 mm x 695 mm x 2300 mm (47.2” x 27.4” x 90.6”) | 1600 mm x 695 mm x 2300 mm (62.9” x 27.4” x 90.6”) | 2000 mm x 695 mm x 2300 mm (78.7” x 27.4” x 90.6”) | ||
With Adjustable Base Stand (Max) | 1200 mm x 695 mm x 2700 mm (47.2” x 27.4” x 106.3”) | 1600 mm x 695 mm x 2700 mm (62.9” x 27.4” x 106.3”) | 2000 mm x 695 mm x 2700 mm (78.7” x 27.4” x 106.3”) | ||
External Dimensions (W x D x H) with 1000 mm Pass Through Chamber | With Pod Flange | With BIBO | 2465 mm x 780 mm x 3000 mm (97.0” x 30.7” x 118.1”) | 2865 mm x 780 mm x 3000 mm (112.8” x 30.7” x 118.1”) | 3265 mm x 780 mm x 3000 mm (128.5” x 30.7” x 118.1”) |
Without BIBO | 2465 mm x 780 mm x 2600 mm (97.0” x 30.7” x 102.4”) | 2865 mm x 780 mm x 2600 mm (112.8” x 30.7” x 102.4”) | 3265 mm x 780 mm x 2600 mm (128.5” x 30.7” x 102.4”) | ||
With Adjustable Base Stand (Min) | 2465 mm x 780 mm x 2300 mm (97.0” x 30.7” x 90.6) | 2865 mm x 780 mm x 2300 mm (112.8” x 30.7” x 90.6”) | 3265 mm x 780 mm x 2300 mm (128.5” x 30.7” x 90.6”) | ||
With Adjustable Base Stand (Max) | 2465 mm x 780 mm x 2700 mm (97.0” x 30.7” x 106.3”) | 2865 mm x 780 mm x 2700 mm (112.8” x 30.7” x 106.3”) | 3265 mm x 780 mm x 2700 mm (128.5” x 30.7” x 106.3”) | ||
Without Pod Flange | With BIBO | 2465 mm x 695 mm x 3000 mm (97.0” x 27.4” x 118.1”) | 2865 mm x 695 mm x 3000 mm (112.8” x 27.4” x 118.1”) | 3265 mm x 695 mm x 3000 mm (128.5” x 27.4” x 118.1”) | |
Without BIBO | 2465 mm x 695 mm x 2600 mm (97.0” x 27.4” x 102.4”) | 2865 mm x 695 mm x 2600 mm (112.8” x 27.4” x 102.4”) | 3265 mm x 695 mm x 2600 mm (128.5” x 27.4” x 102.4”) | ||
With Adjustable Base Stand (Min) | 2465 mm x 695 mm x 2300 mm (97.0” x 27.4” x 90.6”) | 2865 mm x 695 mm x 2300 mm (112.8” x 27.4” x 90.6”) | 3265 mm x 695 mm x 2300 mm (128.5” x 27.4” x 90.6”) | ||
With Adjustable Base Stand (Max) | 2465 mm x 695 mm x 2700 mm (97.0” x 27.4” x 106.3”) | 2865 mm x 695 mm x 2700 mm (112.8” x 27.4” x 106.3”) | 3265 mm x 695 mm x 2700 mm (128.5” x 27.4” x 106.3”) | ||
External Dimensions (W x D x H) with 600 mm Pass Through Chamber | With Pod Flange | With BIBO | 2065 mm x 780 mm x 3000 mm (81.3” x 30.7” x 118.1”) | 2465 mm x 780 mm x 3000 mm (97.0” x 30.7” x 118.1”) | 2865 mm x 780 mm x 3000 mm (112.8” x 30.7” x 118.1”) |
Without BIBO | 2065 mm x 780 mm x 2600 mm (81.3” x 30.7” x 102.4”) | 2465 mm x 780 mm x 2600 mm (97.0” x 30.7” x 102.4”) | 2865 mm x 780 mm x 2600 mm (112.8” x 30.7” x 102.4”) | ||
With Adjustable Base Stand (Min) | 2065 mm x 780 mm x 2300 mm (81.3” x 30.7” x 90.6”) | 2465 mm x 780 mm x 2300 mm (97.0” x 30.7” x 90.6”) | 2865 mm x 780 mm x 2300 mm (112.8” x 30.7” x 90.6”) | ||
With Adjustable Base Stand (Max) | 2065 mm x 780 mm x 2700 mm (81.3” x 30.7” x 106.3”) | 2465 mm x 780 mm x 2700 mm (97.0” x 30.7” x 106.3”) | 2865 mm x 780 mm x 2700 mm (112.8” x 30.7” x 106.3”) | ||
Without Pod Flange | With BIBO | 2065 mm x 695 mm x 3000 mm (81.3” x 27.4” x 118.1”) | 2465 mm x 695 mm x 3000 mm (97.0” x 27.4” x 118.1”) | 2865 mm x 695 mm x 3000 mm (112.8” x 27.4” x 118.1”) | |
Without BIBO | 2065 mm x 695 mm x 2600 mm (81.3” x 27.4” x 102.4”) | 2465 mm x 695 mm x 2600 mm (97.0” x 27.4” x 102.4”) | 2865 mm x 695 mm x 2600 mm (112.8” x 27.4” x 102.4”) | ||
With Adjustable Base Stand (Min) | 2065 mm x 695 mm x 2300 mm (81.3” x 27.4” x 90.6”) | 2465 mm x 695 mm x 2300 mm (97.0” x 27.4” x 90.6”) | 2865 mm x 695 mm x 2300 mm (112.8” x 27.4” x 90.6”) | ||
With Adjustable Base Stand (Max) | 2065 mm x 695 mm x 2700 mm (81.3” x 27.4” x 106.3”) | 2465 mm x 695 mm x 2700 mm (97.0” x 27.4” x 106.3”) | 2865 mm x 695 mm x 2700 mm (112.8” x 27.4” x 106.3”) | ||
Internal Dimensions (W x D x H) | 1192 mm x 630 mm x 842 mm (46.9” x 24.8” x 33.1”) | 1592 mm x 630 mm x 842 mm (62.7” x 24.8” x 33.1) | 1992 mm x 630 mm x 842 mm (78.4” x 24.8” x 33.1) | ||
Chamber Sheet Metal | Stainless Steel Type 316L (interior) Stainless Steel Type 304 (exterior) | ||||
Filter Type | ULPA filter (U15) | ||||
Support Frame & Service Housing | Stainless Steel Type 304 | ||||
Chamber Environment | ISO Class 5 (Grade A) | ||||
Airflow Type | Turbulent | ||||
Lighting Intensity | ≥ 500 Lux (≥ 47 foot-candles) | ||||
Noise Level | ≤ 65 dBA | ||||
Electrical Requirement | AC 230-240 V, 50/60 Hz, 1 Ph, 25A | ||||
